Colby Watkins

Founder-operator. Sunday morning briefing on peptides — without six Discords or bro-science.

GLP-1 Family Decision Tree: Sema vs Tirz vs Reta — When Each Wins

Jun 14, 2026

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6 min read

GLP-1 Family Decision Tree: Sema vs Tirz vs Reta — When Each Wins

Sema vs tirz vs reta. When each wins, what the literature actually shows, no marketing.

Colby Watkins

The Wolverine Stack, Re-examined: What the BPC-157 + TB-500 Literature Actually Says in 2026

Jun 7, 2026

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7 min read

The Wolverine Stack, Re-examined: What the BPC-157 + TB-500 Literature Actually Says in 2026

BPC-157 + TB-500 — what the corpus does and doesn't say. The Wolverine stack, walked through with the tier framework.

Colby Watkins

The 39% Question: Synthesizing the GLP-1 Muscle-Loss Literature

May 31, 2026

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6 min read

The 39% Question: Synthesizing the GLP-1 Muscle-Loss Literature

Harvard Science Review said 39% of weight lost on semaglutide is lean mass. The methodology has been pushed back on for years, and a January 2026 longitudinal study now reads the same phenomenon a different way. The Brief synthesizes the literature, then plants a flag mainstream coverage is missing.

Colby Watkins